Hepatitis D
A new form or hepatitis that is considered to be a widespread treat is “delta hepatitis “ or hepatitis D. Hepatitis D virus is and unusual, single-stranded, circular RNA virus with a number of similarities to certain plant vira satellites and viroids.Hepatitis D is a liver disease in both acute and chronic forms caused by hepatitis D virus that requires HBV for its replication. Hepatitis D virus cannot occur in the absence of hepatitis B virus.HBV-HDV co-infection is considered the most severe form of chronic viral hepatitisdue to more rapid progression towards liver- related death and hepatocellular carcinoma.
Transmission:
The routes of HDV transmission are the same as for HBV
• Percutaneously
• Sexual
• In contact with infected blood or blood products.
• Vertical transmission is possible but rare
Symptoms:
•Symptoms are same as for hepatitis B
• Acute hepatitis
Risk factors:
• High prevalence in persons who inject drugs
• Sex workers
• Migrants from high HDV prevalence countries
• People who are not immune to HBV
Prevention:
•A vaccine against hepatitis B is the only method to prevent HDV infection.
• Blood safety
• Injection safety
Treatment:
• Pegylated interferon alpha for at least 48 weeks.
• Liver transplantation may be considered for cases of fulminant hepatitis and end-stage liver disease.
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